Virtual Poster Session 1

December 1, 2021

Listen to the Q&A.

Áron Györgypál

An Integrated Process Analytical Platform for Automated Monitoring of Monoclonal Antibody N-linked Glycosylation

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Áron Györgypál is a doctoral candidate at Rutgers University in the department of Chemical and Biochemical Engineering.

His research is within continuous biomanufacturing on monoclonal antibody-based biologics. He is working developing and implementing novel process analytical technology (PAT) tools to measure glycosylation, a post translational modification and critical quality attribute that is critical for proper therapeutic manufacturing.
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Garima Thakur
PhD Researcher

PAT strategies for modelling and control of single-pass tangential flow ultrafiltration (SPTFF) in continuous manufacturing of monoclonal antibodies

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Garima is a researcher working under Prof. Anurag Rathore in the Bioprocessing Lab at the Indian Institute of Technology, Delhi.

She works in the area of PAT applications for continuous downstream manufacturing of biopharmaceuticals and has 10+ international publications and 4 related patent filings in the field. Her work is focussed on overcoming the unique challenges associated with continuous operation in the biopharma industry, particularly handling process deviations with real time control tools. She has worked on developing novel PAT tools including data-driven AI-ML solutions and novel spectroscopic tools for improved control of unit operations in the continuous downstream manufacturing train.
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Hemlata Chhabra
Post doctoral fellow

The global landscape on interchangeability of biosimilars

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Hemlata Chhabra is Post doc fellow with Prof. Anurag Rathore at Indian Institute of Technology, Delhi.

Before that, she has worked in company at managerial position. Her current area of research include to understand regulatory and pharmacoeconomic aspects of biosimilars and to make biologics affordable. She has 10 plus publications in peer reviewed journals and one patent.
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Jocelyn M. Jiménez-Cruz
BS

Polymorphism and Solubility Studies in Early Drug Development: The Account of MBQ-167

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Jocelyn M. Jiménez Cruz is currently pursuing a Master of Science in Industrial Pharmacy from the University of Puerto Rico-Medical Sciences Campus under the mentorship of Drs. López-Mejías and Stelzer.

She received her bachelor's degree in Industrial Chemical Processes from the University of Puerto Rico at Arecibo. Miss Jiménez is presently Chair of the American Association of Pharmaceutical Scientists Student Chapter at the University of Puerto Rico. In this role, she aims to provide graduate students tools to enhance their professional development. She has authored two publications regarding the solubility and polymorphism of MBQ-167 which are the topic of today’s presentation.
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Kandarp Dave

Engineered Extracellular Vesicles Transfer Mitochondria and pDNA to Increase Cellular ATP levels in Brain Endothelial Cells

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Kandarp Dave is a graduate student in the Pharmaceutics Department of Graduate School of Pharmaceutical Sciences at Duquesne University.

Manya Mittal

Bio-physical characterization of HPV L1 protein and Virus-like particles

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Manya is pursuing PhD in chemical engineering at UQ - IIT Delhi Academy of research.

She works on purification of virus-like particles and their characterisation using various analytical tools. She was awarded a masters in chemical engineering from Rutgers University, New Jersey and a bachelors degree in pharmaceutical technology from the Institute of Chemical Technology, Mumbai. Manya also has experience in characterisation of pharmaceuticals and is interested in the process analytical tool based control strategies for biopharmaceutical manufacturing.
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Mustafa Bookwala

Interpreting the Physicochemical Meaning of a Molecular Descriptor Predictive of Dispersion Formation in PVPva Co-Polymer

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Mustafa Bookwala is a Ph.D. candidate at Duquesne University, doing research under the guidance of Dr. Peter Wildfong.

Mustafa's dissertation research is to understand the implications of non-covalent interactions on the physical stability of amorphous solid dispersions. Mustafa holds a B.S. in pharmaceutical sciences and an M.S. in pharmaceutics and drug delivery.
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Rahul Lalge
PhD Candidate

The Role of Drug – Polymer Hydrogen Bonding Interactions on the Critical Cooling Rate of Amorphous Solid Dispersions

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Rahul is a 4th year Ph.D. candidate in Pharmaceutics at University of Minnesota, MN currently working with Dr. Raj Suryanarayanan.

He graduated with a master's degree in Pharmaceutical Sciences from University of Mississippi in 2018 and joined the Ph.D. program at UMN. His research involves designing and processing of amorphous pharmaceutical drug products and improving their physical stability.
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Shantanu Banerjee
M. Tech

Mechanistic Modelling of Chinese Hamster Ovary (CHO) cell Continuous Clarification using Acoustic Wave Separation Technology

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Shantanu Banerjee is a PhD scholar at the Department of Chemical Engineering, Indian Institute of Technology Delhi, working under the supervision of Prof. Anurag Rathore.

His thesis is focused on Process Analytical Technology applications in upstream bioprocessing and harvest unit operations. His research interests are modelling and developing PAT tools for real-time metabolite quantification in E. coli and CHO cell cultures. He also works on mechanistic modelling of acoustic cell clarification, process control and continuous process integration of upstream and downstream.
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Shravan Sreenivasan

Rapid Aggregation of Therapeutic IgG by Bubbling Induced Air/Liquid Interfacial Agitation

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Shravan Sreenivasan is currently working as a Ph.D. research scholar in the\n Department of Chemical Engineering at the Indian Institute of Technology Delhi.

As part of the Ph.D, he is working on degradation of therapeutic proteins. Before joining IIT Delhi, he had worked at Curateq Biologics (Aurobindo Pharma), Hyderabad. He has done his M.Tech in Bioprocess Technology from Institute of Chemical Technology, Mumbai and B.Tech in Biochemical Engineering from University of Kerala."}">Shravan Sreenivasan is currently working as a Ph.D. research scholar in the Department of Chemical Engineering at the Indian Institute of Technology Delhi. As part of the Ph.D, he is working on degradation of therapeutic proteins. Before joining IIT Delhi, he had worked at Curateq Biologics (Aurobindo Pharma), Hyderabad. He has done his M.Tech in Bioprocess Technology from Institute of Chemical Technology, Mumbai and B.Tech in Biochemical Engineering from University of Kerala.
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Yuxin Liu
PhD Candidate

Developing an effective approach for microbial biosynthesis of hydroxyhydroquinone

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Ph.D. Candidate in Chemical and Biochemical Engineering at Rutgers University