2020 NIPTE Research Conference Program

Advances in Pharmaceutical Technology and Education

All sessions will be held virtually

December 8-11, 2020

All times are Eastern Standard Time (EST)

This free conference will be held over multiple days to include:
• Educational webinars and special sessions
• Exchange of ideas and best practices
• Award presentations
• Networking
• Research presentations


Tuesday, December 8

All times are Eastern Standard Time (EST)

SESSION 1  |   Conference Welcome & Keynote
08:00 a.m.Conference overview & introductions– Dr. Vadim Gurvich , NIPTE
08:15 a.m.Dr. Ajaz S. Hussain, President, NIPTE — “Industrial Policy and NIPTE
09:00 a.m.Keynote address — Drs. Michael T. Osterholm and Stephen Schondelmeyer, University of Minnesota — “Impact of the Pandemic on Drug Shortages”
09:30 a.m.NIPTE Distinguished Scholars Awards, Dr. Vadim Gurvich, NIPTE
09:50 a.m.Break
PRESENTATIONS   |   NIPTE Distinguished Scholars
10:00 a.m.Dr. Kenneth R. Morris, Professor Emeritus, Long Island University — “Modeling Artifact and Anomalies as a Research Strategy
10:30 a.m.Dr. Ryan Pearson, University of Maryland — “Engineering Nanoparticles for Immunomodulation
11:00 p.m.Hongbo Chen, University of Minnesota — “Improving the Manufacturability and Dissolution Performance of Drugs Through Spherical Cocrystallization
11:30 p.m.Dana Moseson, Purdue University — “Origins of residual crystallinity in hot-melt extruded amorphous solid dispersions and product performance implications
12:00 p.m.Session End  
SESSION 2  |  Nanotechnology
03:00 p.m.Session and speaker introductions – Dr. Aliasger K. Salem, University of Iowa
03:10 p.m.Dr. Xiaoming Xu, Lab Chief (acting), Office of Pharmaceutical Quality, FDA — “Supporting the Development of Drug Products Containing Nanomaterials: Guidance, Trends, and Research
03:30 p.m.Dr. Zhengrong Cui, University of Texas at Austin — “Thin-film freeze-drying vaccines for cold chain- and needle-free vaccination
04:00 p.m.Dr. Devika S. Manickam, Duquesne University — “Cell-derived Extracellular Vesicles and Lipidoid Nanoparticles for CNS Drug Delivery
04:30 p.m.Emad Ibrahim Wafa, University of Iowa — “Polymeric Particles as Pancreatic Cancer Vaccine Vectors
04:50 p.m.André O’Reilly Beringhs, PhD Candidate, University of Connecticut — “Imaging Tumors using X-ray Computed Tomography through Nanocapsule-based Contrast Agent
05:10 p.m.Panel / Q&A — Dr. Xiuling Lu, University of Connecticut, moderator
05:30 p.m.Session end

Wednesday, December 9

All times are Eastern Standard Time (EST)

SESSION 1   |   Advanced Manufacturing
08:00 a.m.Session and speaker introductions — Dr. Ira Buckner, Duquesne University
08:15 a.m.Dr. Thomas O’Connor, Division of Product Quality Research, FDA — “The Role of Advanced Manufacturing in Addressing Current Industry & Patient Needs
08:35 a.m.Dr. David Thompson, Purdue University — “Optimization of Continuous API Manufacture, Guided by High-Throughput Experimentation”
08:55 a.m.Dr. Diane Burgess, University of Connecticut — “Continuous Manufacturing of Complex Parenterals”
09:15 a.m.Dr. Fernando Muzzio, Rutgers University — “An integrated design framework for advanced pharmaceutical manufacturing”
09:35 a.m.Dr. Frank Gupton, Virginia Commonwealth University — “Ensuring Access to Healthcare in a Post-Pandemic World
10:00 a.m.Panel / Q&A — Dr. Michael Repka, University of Mississippi, moderator
10:20 a.m.Session End
PRESENTATIONS  |  Student Research
12:00 p.m.Mustafa Bookwala, Duquesne University — “Crystal Structure Solution for Terfenadine Allows Prediction of its Mechanical Disordering during Milling”
12:15 p.m.Devang Patel, Long Island University — “Predicting the effect of tablet lubricant on occurrence of tablet sticking during tablet production using powder rheometer”
12:30 p.m.Karishma Dhuri, University of Connecticut — “Targeting Multiple OncomiRs: Next Generation Precision Medicine for Lymphoma Therapy”
12:45 p.m.Ashwini Gumireddy, Duquesne University — “Investigating the Applicability of the Molecular Descriptor R3m in Predicting Amorphous Solid Dispersion Formation for Thermally Unstable APIs”
01:00 p.m.Kandarp Dave, Duquesne University — “Development of safe and efficient zwitterionic polymer-based Interferon-β1 DNA polyplexes for glioblastoma therapy”
01:30 p.m.Session End
SESSION 2   |   Ajaz S. Hussain Tribute
03:00 p.m.Session and speaker introductionsDr. Vadim J. Gurvich, NIPTE
03:15 p.m.Dr. Robin Bogner, University of Connecticut — “Ajaz Hussain: The Tao of Pharmaceuticals”
03:35 p.m.Dr. Kenneth R. Morris, Professor Emeritus, Long Island University — “Ajaz Hussain: the Conscience of Our Community
03:55 p.m.Dr. Stephen R. Byrn, Purdue University — “Ajaz S. Hussain: Quality Guru
04:15 p.m.Dr. Ajaz S. Hussain
04:35 p.m.Virtual Reception
05:00 p.m.Session End

Thursday, December 10

All times are Eastern Standard Time (EST)

SESSION 1  |   Quality Scorecards / Index
08:30 a.m.Session and speaker introductionsDr. John Gray, Ohio State University
08:45 a.m.Dr. Stephen R. Byrn, Purdue University — “Initial Investigation of Drug Formulation-Based Recalls
09:15 a.m.Dr. Rahul Haware, Long Island University — “Multivariate Approach for Decoding Responsible Drug Molecular Descriptors for Product Recalls
09:45 a.m.Panel / Q&A
10:00 a.m.Session End
PRESENTATIONS   |   Student Research
12:00 p.m.Gerrit Vreeman, University of Minnesota — “Salt formation for improved tabletability despite reduced plasticity”
12:15 p.m.Shipra Malik, University of Connecticut — “Discoidal Nano Universal Platform for Efficient Delivery of PNAs”
12:30 p.m.Raqeeb Jamil, University of Maryland — “Similarity of dissolution profiles from biorelevant media: Assessment of interday repeatability, interanalyst repeatability, and interlaboratory reproducibility using ibuprofen and ketoconazole tablets”
12:45 p.m.Wei-Chung Luo, University of Connecticut — “Impact of lyoprotectants and freezing variations on the stability of nanoparticles”
01:00 p.m. Jayesh Sonje, University of Minnesota — “Insitu investigation of freeze-thaw induced LDH aggregation in sodium phosphate buffer using neutron scattering”
01:15 p.m.Navpreet Kaur, University of Minnesota — “Partial dehydration of levothyroxine sodium pentahydrate in a drug product environment: Implications on chemical stability”
01:30 p.m.Session End
SESSION 2   | Emerging Areas in Pharmaceutical Sciences
03:00 p.m. Dr. James Polli, University of Maryland — “Introducing Complex Generics Center
03:30 p.m.Eyal Barash, JD, MS, BS, BA, Barash Law — “Intellectual Property in Pharma: General Principles for the Research Scientist
03:55 p.m.Dr. Mudassir Rashid, Illinois Institute of Technology — “Advanced Manufacturing of Biopharmaceuticals: Model Learning and Predictive Control
04:15 p.m.Session End

Friday, December 11

All times are Eastern Standard Time (EST)

SESSION 1   |   Knowledge Management and New Prior Knowledge
08:00 a.m.Session and speaker introductions — Dr. Kenneth R. Morris, Professor Emeritus, Long Island University
08:15 a.m.Dr. Gintaras Reklaitis, Purdue University — “Knowledge Sharing and Management in support of development and manufacturing
08:35 a.m.Dr. Douglas B. Hausner, Senior Manager, Continuous Manufacturing Business Development, OSD, Patheon Pharma Services, part of Thermo Fisher Scientific — “Knowledge Management in Continuous Solid Dose Manufacturing at Thermo Fisher Scientific
08:55 a.m.Dr. Fernando Muzzio, Rutgers University and Dr. Atul Dubey, Director, Pharmaceutical Continuous Manufacturing (PCM), USP — A Knowledge Management Framework for Pharmaceutical Product and Manufacturing Process Design
09:35 a.m.Panel / Q&A
10:00 a.m.Session End
SESSION 2   |   Abuse Deterrent Formulations
03:00 p.m. Session and speaker introductionsDr. Stephen R. Byrn, Purdue University
03:10 p.m.Dr. Heather Boyce, Office of Generic Drugs, Food and Drug Administration — “Pharmacokinetics of milled oxycodone hydrochloride tablet products following nasal insufflation in nondependent, recreational opioid users
03:45 p.m.Dr. Ziyaur Rahman, Texas A&M University — “Understanding Science of Meth-Deterrent Formulations
04:10 p.m.Dr. Feng Zhang, University of Texas at Austin — “Dow Chemical vs. Sumitomo Seika PEO, How does the difference impact product quality of ADF?”
04:35 p.m.Panel / Q&A — Dr. Stephen R. Byrn, Purdue University, moderator
05:00 p.m.Closing Remarks — Dr. Xiuling Lu, University of Connecticut
05:15 p.m.Conference End