Current Research

Further development of nonlinear optical imaging for sensitive detection of Crystallinity in Amorphous Powders

  • Lead: Taylor
  • Institution: Purdue

Development of Real-time Release Continuous Crystallization System with Anticrust Control

  • Lead: Nagy
  • Institution: Purdue

Particle Size Distribution Equivalency using Novel Statistical Comparator and PBPK Input Models

  • Lead: Kirsch
  • Institution: Iowa

Determination of Local Concentrations of Bupivacaine using Microdialysis Techniques

  • Lead: Berkland
  • Institution: Kansas

Multi-scale Model Development and Validation of Fluid Bed Granualtion (FBG) Processes to Facilitate QbD and Scale-up in Pharmaceutical Drug Product Manufacturing

  • Lead: Ramachandra
  • Institution: Rutgers

 

Transdermal drug delivery systems - Fentanyl

  • Lead: Stinchcomb
  • Institution: University of Maryland

 

Transdermal drug delivery systems - Fentanyl

  • Lead: Brogden
  • Institution: University of Iowa

Critical path manufacturing sector research initiave

  • Lead: Gurvich
  • Institution: University of Minnesota

QBD approach to process development: defining critical quality attributes, evaluation criticality across scales, and relating variation in cpps/cqas to product performance

  • Lead: Drennen
  • Institution: Duquesne University

 

Transdermal Drug Delivery Systems - Oxybutynin

  • Lead: Brogeden
  • Institution: University of Iowa

Exploring performance variability in dissolution testing using biorelevant media

  • Lead: Morris
  • Institution: Long Island University

Identification of chemical enhancer specification requirements for TDDS

  • Lead: Stinchcomb
  • Institution: University of Maryland, Balitimore

 

Exploring performance variability in dissolution testing using biorelevant media

  • Lead: Polli
  • Institution: University of Maryland, Baltimore

Transdermal drug delivery systems - Oxybutynin

  • Lead: Kandimalla
  • Institution: University of Minnesota

Inter-relations between spray drying process parameters and product performance for formulations of poorly water soluble compounds

  • Lead: Taylor
  • Institution: Purdue University

 

Inter-relations between spray drying process parameters and product performance for formulations of poorly water soluble compounds

  • Lead: Marsac
  • Institution: University of Kentucky

Effect of formulation and process variations on aggregation in model theraperutic proteins: impact of scale-up

  • Lead: Pikal
  • Institution: University of Connecticut

Effect of formulation and process variations on aggregation in model theraperutic proteins: impact of scale-up

  • Lead: Alexeenko
  • Institution: Purdue University

 

Patient acceptance of drugs

  • Lead: Hoag
  • Institution: University of Maryland

Dissolution and bioequivalence of poorly soluable active pharmaceutical ingredients formulated as amorphous solid dispersion systems

  • Lead: Marsac
  • Institution: University of Kentucky

 

Biosimilars Group

Analytical Comparison of Parent and Follow-On Biologics to Aid Biosimilars Regulatory Guidelines Development

  • Lead: Anna Schwendeman
  • Institution: University of Michigan

Physiochemical and Biological Evalutations of Different IgG1Fc Glycoforms as a Model of Biosimilar Comparability Analysis

  • Lead: Thomas Tolbert
  • Institution: University of Kansas

 

Sterilization

Sterilization Process Development for Pre-Operative Anitseptic Products

  • Lead: Ed Elder
  • Institution: University of Wisconsin